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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 847912Generated: November 1, 2026

Benzoyl isothiocyanate → N-benzoyl-N'-[2-(2-benzimidazolylmethylthio)ethyl]thiourea

https://huagongshe.com/reaction/847912

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBenzoyl isothiocyanateHCID 68284—
Reactant2-[(2-Aminoethyl)thiomethyl]benzimidazoleHCID 12923420—
ProductN-benzoyl-N'-[2-(2-benzimidazolylmethylthio)ethyl]thioureaHCID 54046077—

Reaction Steps

Benzoyl isothiocyanate is reacted with 2-[(2-aminoethyl)thiomethyl]benzimidazole by the procedure of Example 18 to give N-benzoyl-N'-[2-(2-benzimidazolylmethylthio)ethyl]thiourea. Removing the benzoyl group by the procedure of Example 18 gives N-[2-(2-benzimidazolylmethylthio)ethyl]thiourea.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04293697
Source datasetuspto-grants-1981_10
ORD IDord-0f69fd19ffdb493fbc36e33d78479b06
Source noteuspto-grants-1981_10