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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 848002Generated: October 30, 2026

Ethyl isothiocyanate → N-ethyl-N'-[2-(2-thiazolylmethylamino)ethyl]thiourea

https://huagongshe.com/reaction/848002

Reaction equation

Participants

RoleNameHCIDCharge
ReactantEthyl isothiocyanateHCID 10966—
ReactantN-(2-thiazolylmethyl)ethylenediamineHCID 17944882—
ProductN-ethyl-N'-[2-(2-thiazolylmethylamino)ethyl]thioureaHCID 20567447—

Reaction Steps

Reacting N-(2-thiazolylmethyl)ethylenediamine with ethyl isothiocyanate by the procedure of Example 3(b) and then chromatographing gives N-ethyl-N'-[2-(2-thiazolylmethylamino)ethyl]thiourea. Reacting this thiourea with lead cyanamide by the procedure of Example 3(b) gives N-cyano-N'-ethyl-N"-[2-(2-thiazolylmethylamino)ethyl]guanidine.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04293699
Source datasetuspto-grants-1981_10
ORD IDord-aeb2fe6241b94a5e8fc002f34ccf159f
Source noteuspto-grants-1981_10