Ethyl isothiocyanate → HCID 178464583, compound

HRID 848021Notes

Reaction equation

[N:1]1[C:5]2[CH:6]=[CH:7][CH:8]=[CH:9][C:4]=2[NH:3][C:2]=1[CH2:10][NH:11][CH2:12][CH2:13][NH2:14].[CH2:15]([N:17]=[C:18]=S)[CH3:16].[NH2:20][C:21]([NH2:23])=S.N#CN.[Pb]>>[N:1]1[C:5]2[CH:6]=[CH:7][CH:8]=[CH:9][C:4]=2[NH:3][C:2]=1[CH2:10][NH:11][CH2:12][CH2:13][NH:14][C:18]([NH:23][C:21]#[N:20])=[N:17][CH2:15][CH3:16]

Participants

Reactant 4

HCID 10966Ethyl isothiocyanate

HCID 2723790Thiourea

HCID 15365342N1-((1H-Benzo[d]imidazol-2-yl)methyl)ethane-1,2-diamine

HCID 22262466CH2N2Pb

Product 1

HCID 178464583HCID 178464583, compound

Procedure

Reacting N-(2-benzimidazolylmethyl)ethylenediamine with ethyl isothiocyanate by the procedure of Example 3(b), then chromatographing and reacting the resulting thiourea with lead cyanamide by the procedure of Example 3(b) gives N-[2-(2-benzimidazolylmethylamino)ethyl]-N'-cyano-N"-ethylguanidine.

Sources & evidence

ORD record: ord-b8fe03c4e459494985915d6ec5728567
Source dataset: uspto-grants-1981_10
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04293699

Reaction notes

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