HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 12833268, compound → 1-(3'-Amino-4',6'-dimethylphenyl)azetidin-2-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 12833268 | HCID 12833268 | — |
| Catalyst | Nickel | HCID 935 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | 1-(3'-Amino-4',6'-dimethylphenyl)azetidin-2-one | HCID 12833270 | 90.4% |
Reaction Steps
21.2 g (0.0965 mol) of the 1-(3'-nitro-4',6'-dimethylphenyl)-azetidin-2-one obtained according to (a) are hydrogenated in 210 ml of methanol with 2 g of Raney nickel at 30°-35° under normal pressure. The reaction solution is filtered and evaporated. Recrystallisation of the crude product from methanol gives 16.6 g (90%) of crystals having a melting point of 123°-124°.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04294606 |
| Source dataset | uspto-grants-1981_10 |
| ORD ID | ord-36d1446ec5f04e90a3d30f9b3a624361 |
| Source note | uspto-grants-1981_10 |