HuagongsheHuagongshe Chemistry Print Report · For research reference only
1,3-Dichloro-4,6-dinitrobenzene → 4,6-Dichlorobenzene-1,3-diamine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1,3-Dichloro-4,6-dinitrobenzene | HCID 77286 | — |
| Catalyst | Nickel | HCID 935 | — |
| Solvent | 1,4-Dioxane | HCID 31275 | — |
| Product | 4,6-Dichlorobenzene-1,3-diamine | HCID 3372869 | — |
Reaction Steps
87.0 g (0.37 mol) of 1,3-dichloro-4,6-dinitrobenzene are dissolved in 1.5 liters of dioxane and, after adding a total of 100 g of Raney Ni, hydrogenated at 40° to 80° C. The catalyst is filtered off and washed with dioxane and the filtrate is concentrated. The product obtained in this way is recrystallised from hexane/toluene. Yield: 40.6 g; melting point 138°-141° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04294606 |
| Source dataset | uspto-grants-1981_10 |
| ORD ID | ord-4222ef22dd51420398fd25f88472582e |
| Source note | uspto-grants-1981_10 |