Diethylaminoethyl chloride → HCID 20566268, compound

HRID 848068Notes

Reaction equation

[O:1]1[CH:5]=[CH:4][CH:3]=[C:2]1[S:6]([C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=1)(=[NH:8])=[O:7].[CH2:15]([N:17]([CH2:21][CH3:22])[CH2:18][CH2:19]Cl)[CH3:16]>>[CH2:15]([N:17]([CH2:21][CH3:22])[CH2:18][CH2:19][N:8]=[S:6]([C:2]1[O:1][CH:5]=[CH:4][CH:3]=1)([C:9]1[CH:10]=[CH:11][CH:12]=[CH:13][CH:14]=1)=[O:7])[CH3:16]

Participants

Reactant 2

HCID 13364Diethylaminoethyl chloride

HCID 20566256HCID 20566256, compound

Product 1

HCID 20566268HCID 20566268, compoundYield 48%

Procedure

In a manner analogous to that described in Example 1, Stage 3, from S-(2-furyl)-S-phenyl-sulphoximide and 2-diethylaminoethyl chloride, there is obtained N-(2-diethylaminoethyl-S-(2-furyl)-S-phenyl-sulphoximide in a yield of 48% of theory. The corresponding fumarate, after recrystallisation from ethyl acetate/isopropanol, melts at 133° C.

Sources & evidence

ORD record: ord-676c03f1eb4a4ba4b02cc92b4bb7faf7
Source dataset: uspto-grants-1981_10
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04294838

Reaction notes

Loading…