HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → 4-[3-(4-Fluorophenyl)propyl]piperidine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | 3-(1-Benzoyl 4-piperidyl) 1-(4-fluorophenyl) 1-propanone | HCID 54515714 | — |
| Product | 4-[3-(4-Fluorophenyl)propyl]piperidine | HCID 3059022 | 55.1% |
Reaction Steps
The procedure is as in Example 6 starting from 24.2 g of 3-(1-benzoyl 4-piperidyl) 1-(4-fluorophenyl) 1-propanone. 8.7 g of 4-[3-(4-fluorophenyl)1-propyl]piperidine are obtained in the form of the hydrochloride melting at 142° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04294841 |
| Source dataset | uspto-grants-1981_10 |
| ORD ID | ord-0f975272f4e940d5a0cf21a999f3db18 |
| Source note | uspto-grants-1981_10 |