Benzenamine, 2-((1,2,4-oxadiazol-3-ylmethyl)thio)- → HCID 178507521, compound

Participants

Reaction Steps

To a solution of 3-(2-aminophenylthiomethyl)1,2,4-oxadiazole (3.1 g, 0.015 mol) in dry methanol was added sodium borohydride (1.72 g) at 0° in aliquots over 2 hours, with stirring. After standing at 0° overnight a white precipitate had formed. The crude product was recovered by filtration and re-crystallised from ethanol to give 3-(2-aminophenylthiomethyl)-4,5-dihydro-1,2,4-oxadiazole, m.p. 108°.

Provenance & Evidence