HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetic Anhydride → 2-(2-Formamidothiazol-4-yl)-2-isobutoxyiminoacetic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetic Anhydride | HCID 7918 | — |
| Reactant | 2-(2-Aminothiazol-4-yl)-2-isobutoxyiminoacetic acid | HCID 53968178 | — |
| Solvent | Formic Acid | HCID 284 | — |
| Product | 2-(2-Formamidothiazol-4-yl)-2-isobutoxyiminoacetic acid | HCID 53962534 | 86.9% |
Reaction Steps
2-(2-Aminothiazol-4-yl)-2-iso-butoxyiminoacetic acid (syn isomer, 11.5 g.), acetic anhydride (19.3 g.) and formic acid (8.7 g.) were treated in a similar manner to that of Example F-(5) to give 2-(2-formamidothiazol-4-yl)-2-iso-butoxyiminoacetic acid (syn isomer, 11.15 g.), mp 163° C. (dec.).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04294960 |
| Source dataset | uspto-grants-1981_10 |
| ORD ID | ord-ac46e42ef5084082a7325a049be55802 |
| Source note | uspto-grants-1981_10 |