HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetic Anhydride → 2-(2-Formamidothiazol-4-yl)-2-pentyloxyiminoacetic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetic Anhydride | HCID 7918 | — |
| Reactant | 2-(2-Aminothiazol-4-yl)-2-pentyloxyiminoacetic acid | HCID 54540176 | — |
| Solvent | Formic Acid | HCID 284 | — |
| Product | 2-(2-Formamidothiazol-4-yl)-2-pentyloxyiminoacetic acid | HCID 53807478 | 88.4% |
Reaction Steps
2-(2-Aminothiazol-4-yl)-2-pentyloxyiminoacetic acid (syn isomer, 15 g.), acetic anhydride (23.8 g.) and formic acid (10.7 g.) were treated in a similar manner to that of Example F-(5) to give 2-(2-formamidothiazol-4-yl)-2-pentyloxyiminoacetic acid (syn isomer, 14.7 g.), mp 125° C. (dec.).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04294960 |
| Source dataset | uspto-grants-1981_10 |
| ORD ID | ord-7bc5ae9b977d47ca88cf3726337a0d93 |
| Source note | uspto-grants-1981_10 |