HuagongsheHuagongshe Chemistry Print Report · For research reference only
Thiourea → 7-[2-(2-Amino-4-thiazolyl)-2-methoxyiminoacetamido]-3-cephem-4-carboxylic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Thiourea | HCID 2723790 | — |
| Reactant | 7-(2-Methoxyimino-3-oxo-bromobutyramido)-3-cephem-4-carboxylic acid | HCID 131712504 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 7-[2-(2-Amino-4-thiazolyl)-2-methoxyiminoacetamido]-3-cephem-4-carboxylic acid | HCID 131712444 | — |
Reaction Steps
Thiourea (11 mg.) and a solution of 7-[2-(2-bromoacetyl)-2-methoxyiminoacetamido]-3-cephem-4-carboxylic acid (syn isomer, 30 mg.) in ethanol (2 ml.) were treated in a similar manner to that of Example 36-(4) to give 7-[2-(2-amino-4-thiazolyl)-2-methoxyiminoacetamido]-3-cephem-4-carboxylic acid (syn isomer). The product was identified with an authentic sample by thin layer chromatography.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04294960 |
| Source dataset | uspto-grants-1981_10 |
| ORD ID | ord-9e18ff75dba845c385a5dc885be2d36a |
| Source note | uspto-grants-1981_10 |