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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 848387Generated: October 30, 2026

Hydrochloric Acid → HCID 131712507, compound

https://huagongshe.com/reaction/848387

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantTetrahydrofuranHCID 8028—
ReactantHCID 131712508HCID 131712508—
SolventMethanolHCID 887—
ProductHCID 131712507HCID 131712507—

Reaction Steps

7-[2-(2-Formamidothiazol-4-yl)-4-n-octyloxyiminoacetamido]-3-cephem-4-carboxylic acid (syn isomer, 8.0 g.), conc. hydrochloric acid (6.23 g.), tetrahydrofuran (15 ml.) and methanol (120 ml.) were treated in a similar manner to that of Example 21-(3) to give 7-[2-(2-aminothiazol-4-yl)-2-n-octyloxyiminoacetamido]-3-cephem-4-carboxylic acid (syn isomer, 6.95 g.).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04294960
Source datasetuspto-grants-1981_10
ORD IDord-0c2c785ecfa241609d6ea296e4eb0fb5
Source noteuspto-grants-1981_10