HuagongsheHuagongshe Chemistry Print Report · For research reference only
N-Methylcaprolactam → hexahydro-3-(3-hydroxyphenyl)-1-methyl-2H-azepin-2-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | N-Methylcaprolactam | HCID 17369 | — |
| Reactant | m-Triphenylsiloxybenzyne | HCID 20565338 | — |
| Product | hexahydro-3-(3-hydroxyphenyl)-1-methyl-2H-azepin-2-one | HCID 11746121 | — |
Reaction Steps
Following the procedure of Example 3, reaction of the lithium anion of N-methylcaprolactam with m-triphenylsiloxybenzyne (from o-chlorotriphenylsilyloxybenzene and lithium tetramethylpiperidide) followed by workup with aqueous acid gives the title compound m.p. 192°-3° C. (ethylacetate).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04296029 |
| Source dataset | uspto-grants-1981_10 |
| ORD ID | ord-03a3805f45fa46da86d8dcc88f727809 |
| Source note | uspto-grants-1981_10 |