HRID848419

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID1110

Butanedioic acid

C4H6O4

结构：O=C1c2c(O)ccc(O)c2C(=O)c2c(NCCNCCO)ccc(NCCNCCO)c21

HCID4212

Mitoxantrone

C22H28N4O6

PRODUCTS

生成物

结构：O=C(O)CCC(=O)O.O=C(O)CCC(=O)O.O=C1c2c(O)ccc(O)c2C(=O)c2c(NCCNCCO)ccc(NCCNCCO)c21

HCID86736915

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

溶剂HCID702

Ethanol

C2H6O

PROCEDURE

实验过程

A mixture of 222 mg. of 1,4-bis[2-(2-hydroxyethylamino)ethylamino]-5,8-dihydroxyanthraquinone, 118 mg. of succinic acid, and 50 ml. of ethanol is heated under reflux for 30 minutes to give the title compound.

WORKUP

后处理

additionA mixture of 222 mg
temperatureunder reflux for 30 minutes

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-ec0cc3a8d0de4aa8b8354903c7954143
来源数据集: uspto-grants-1981_10
DOI: 10.6084/m9.figshare.5104873.v1
专利: US04296030
来源说明: uspto-grants-1981_10

反应 SMILES

[OH:1][CH2:2][CH2:3][NH:4][CH2:5][CH2:6][NH:7][C:8]1[C:21]2[C:20](=[O:22])[C:19]3[C:14](=[C:15]([OH:24])[CH:16]=[CH:17][C:18]=3[OH:23])[C:13](=[O:25])[C:12]=2[C:11]([NH:26][CH2:27][CH2:28][NH:29][CH2:30][CH2:31][OH:32])=[CH:10][CH:9]=1.[C:33]([OH:40])(=[O:39])[CH2:34][CH2:35][C:36]([OH:38])=[O:37]>C(O)C>[C:33]([OH:40])(=[O:39])[CH2:34][CH2:35][C:36]([OH:38])=[O:37].[C:33]([OH:40])(=[O:39])[CH2:34][CH2:35][C:36]([OH:38])=[O:37].[OH:1][CH2:2][CH2:3][NH:4][CH2:5][CH2:6][NH:7][C:8]1[C:21]2[C:20](=[O:22])[C:19]3[C:14](=[C:15]([OH:24])[CH:16]=[CH:17][C:18]=3[OH:23])[C:13](=[O:25])[C:12]=2[C:11]([NH:26][CH2:27][CH2:28][NH:29][CH2:30][CH2:31][OH:32])=[CH:10][CH:9]=1