Ethylamine → N-Ethyl-1-isopropylcyclohexanecarboxamide

Participants

Reaction Steps

1-isopropylcyclohexanoyl chloride was prepared from 1-isopropylcyclohexanoic acid and thionyl chloride. A solution of this acid chloride (2.6 g) in ether (25 ml) was added dropwise to a stirred solution of ethylamine (5 ml of a 70% solution in water) in ether (100 ml). After 2 hours the ethereal solution was washed with dilute hydrochloric acid and water, dried (MgSO4) and concentrated to give a white solid. This was recrystallised from petroleum ether (bp. 40°-60°) to give N-ethyl-1-isopropylcyclohexanamide, mp. 101°-2°.

Provenance & Evidence