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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 848450Generated: October 27, 2026

4-keto-L-proline hydrobromide → 1-[3-(acetylthio)-2-methylthio-1-oxopropyl]-4-oxo-L-proline

https://huagongshe.com/reaction/848450

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-keto-L-proline hydrobromideHCID 12773661—
Reactant1-[3-(Acetylthio)-1-oxopropyl]-4-oxo-L-prolineHCID 12773663—
Reactant3-(Acetylthio)-2-(methylthio)propionic acid chlorideHCID 54341183—
Product1-[3-(acetylthio)-2-methylthio-1-oxopropyl]-4-oxo-L-prolineHCID 53685766—

Reaction Steps

The 3-(acetylthio)-2-(methylthio)propionic acid chloride is reacted with 4-keto-L-proline, hydrobromide according to the procedure of Example 1 (d) to yield 1-[3-(acetylthio)-2-methylthio-1-oxopropyl]-4-oxo-L-proline.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04296113
Source datasetuspto-grants-1981_10
ORD IDord-7271890ab7104b30a6abfee5b148698f
Source noteuspto-grants-1981_10