Ammonia → HCID 57127150, compound

HRID 848457Notes

Reaction equation

C([S:4][CH2:5][CH:6]([CH2:18][CH3:19])[C:7]([N:9]1[CH2:16][C:15](=[O:17])[CH2:14][C@H:10]1[C:11]([OH:13])=[O:12])=[O:8])(=O)C.N>>[SH:4][CH2:5][CH:6]([CH2:18][CH3:19])[C:7]([N:9]1[CH2:16][C:15](=[O:17])[CH2:14][C@H:10]1[C:11]([OH:13])=[O:12])=[O:8]

Participants

Reactant 2

HCID 222Ammonia

HCID 57102486HCID 57102486, compound

Product 1

HCID 57127150HCID 57127150, compound

Procedure

The product from part (a) is hydrolyzed with concentrated ammonia according to the procedure of Example 2 to yield (S)-1-(3-mercapto-2-ethyl-1-oxopropyl)-4-oxo-L-proline.

Sources & evidence

ORD record: ord-4cda140039a546c1aa0dcdcdbed13a9c
Source dataset: uspto-grants-1981_10
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04296113

Reaction notes

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