HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-oxo-L-proline → 1-[3-[[(4-methoxy)phenylmethyl]thio]-2-trifluoromethyl-1-oxopropyl]-4-oxo-L-proline
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-oxo-L-proline | HCID 107541 | — |
| Reactant | 3-[[(4-Methoxy)phenylmethyl]thio]-2-trifluoromethylpropionyl chloride | HCID 12941229 | — |
| Product | 1-[3-[[(4-methoxy)phenylmethyl]thio]-2-trifluoromethyl-1-oxopropyl]-4-oxo-L-proline | HCID 22817840 | — |
Reaction Steps
The 3-[[(4-methoxy)phenylmethyl]thio]-2-trifluoromethylpropionyl chloride from part (a) is reacted with 4-keto-L-proline to yield 1-[3-[[(4-methoxy)phenylmethyl]thio]-2-trifluoromethyl-1-oxopropyl]-4-oxo-L-proline.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04296113 |
| Source dataset | uspto-grants-1981_10 |
| ORD ID | ord-a7ad1ab91c97446fa6146ccfa5af3630 |
| Source note | uspto-grants-1981_10 |