HuagongsheHuagongshe Chemistry Print Report · For research reference only
Phenylglyoxylic Acid → 1-(4-Chlorophenyl)-3-phenylquinoxalin-2(1H)-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Phenylglyoxylic Acid | HCID 11915 | — |
| Reactant | N-(4-chlorophenyl)benzene-1,2-diamine | HCID 522323 | — |
| Solvent | Diethyl Ether | HCID 3283 | — |
| Product | 1-(4-Chlorophenyl)-3-phenylquinoxalin-2(1H)-one | HCID 13381305 | — |
Reaction Steps
To a solution of N-(4-chlorophenyl)benzene-1,2-diamine (12.0 g) in a minimum quantity of ether was added benzoylformic acid (7.5 g) dissolved in ether and the mixture was stirred for 8 hours. The resulting precipitate was filtered, dried, and recrystallised from ethanol giving the title compound (11.0 g) mp 214.5°-216.5° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04296114 |
| Source dataset | uspto-grants-1981_10 |
| ORD ID | ord-b0d02b3b78e2433f8ecf759c0b52b500 |
| Source note | uspto-grants-1981_10 |