HuagongsheHuagongshe Chemistry Print Report · For research reference only
Water → 3-Chloro-1-(4-chlorophenyl)-1,2-dihydroquinoxalin-2-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Water | HCID 962 | — |
| Reactant | Phosphorus oxychloride | HCID 24813 | — |
| Reactant | HCID 178516908 | HCID 178516908 | — |
| Product | 3-Chloro-1-(4-chlorophenyl)-1,2-dihydroquinoxalin-2-one | HCID 20565466 | — |
Reaction Steps
A solution of 1-(4-chlorophenyl)-1,2-dihydro-3-hydroxyquinoxalin-2-one (20 g) in phosphorus oxychloride (64 ml) was refluxed for 4 hours and then poured slowly into iced water. The resulting solid was filtered off, triturated with pentane and dried giving the title compound (19.4 g) mp>300° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04296114 |
| Source dataset | uspto-grants-1981_10 |
| ORD ID | ord-59d8c5b2afc34b60b6b84be15093f529 |
| Source note | uspto-grants-1981_10 |