HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ammonium Acetate → 3-Amino-1-(4-chlorophenyl)-1,2-dihydroquinoxalin-2-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ammonium Acetate | HCID 517165 | — |
| Reactant | 1-(4-Chlorophenyl)-1,2-dihydro-3-ethoxyquinoxalin-2-one | HCID 20565453 | — |
| Solvent | Water | HCID 962 | — |
| Product | 3-Amino-1-(4-chlorophenyl)-1,2-dihydroquinoxalin-2-one | HCID 20565482 | 70.4% |
Reaction Steps
To a melt of ammonium acetate (62 g) at 160° C. was added 1-(4-chlorophenyl)-1,2-dihydro-3-ethoxyquinoxalin-2-one (8.8 g) and the temperature was then raised during 5 minutes to 200° C. and maintained at this level for 15 minutes. The melt was cooled, water was added, and the product was filtered off. Crystallisation from ethanol gave the title compound (5.6 g) mp 254°-255° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04296114 |
| Source dataset | uspto-grants-1981_10 |
| ORD ID | ord-6a044e9c5d98424e8147b462d0d79187 |
| Source note | uspto-grants-1981_10 |