HuagongsheHuagongshe Chemistry Print Report · For research reference only
Water → 1-(4-Chlorophenyl)-1,2-dihydro-3-(N-piperidyl)quinoxalin-2-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Water | HCID 962 | — |
| Reactant | Piperidine | HCID 8082 | — |
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | 3-Chloro-1-(4-chlorophenyl)-1,2-dihydroquinoxalin-2-one | HCID 20565466 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 1-(4-Chlorophenyl)-1,2-dihydro-3-(N-piperidyl)quinoxalin-2-one | HCID 20565489 | — |
Reaction Steps
A solution of 3-chloro-1-(4-chlorophenyl)-1,2-dihydroquinoxalin-2-one (7.5 g), piperidine (2.4 g), and triethylamine (2.9 g) in ethanol (50 ml) was stirred at 20° C. for 2 hours. Water was added and the product was extracted into chloroform. Evaporation of the solvent and recrystallisation from ethanol gave the title compound mp 184°-185° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04296114 |
| Source dataset | uspto-grants-1981_10 |
| ORD ID | ord-e4921bda3faf46709a582a9c16f64894 |
| Source note | uspto-grants-1981_10 |