HCID 54539058, compound → HCID 131712512, compound

Participants

Reaction Steps

1.133 Grams (0.00245 mole) of silver salt of chondrosine was dissolved in 70 ml of DMSO (dimethylsulfoxide) and 0.84 g of the compound (1) was added to the solution to react them at room temperature for 2 days. After the reaction, AgBr was separated by a centrifugal separation and DMSO was distilled off from the resulting supernatant at 45° to 50° C. under a reduced pressure and then, 70 ml of ethanol was added to the residual solid and a floating insoluble material was separated and a filtrate was concentrated under a reduced pressure and poured into 2 ml of cold water to precipitate the product. The precipitate was dried and washed with ether and dried to obtain 0.36 g of a conjugate of chondrosine-dehydroepiandrosterone having the formula ##STR1##

Provenance & Evidence