Sodium Methoxide → HCID 178425907, compound

HRID 848639Notes

Reaction equation

HRID 848639 reaction equation
[CH3:1][C:2]1[CH:19]=[CH:18][C:5]([C:6]([O:8][CH2:9][N:10]2[C:15](=[O:16])[NH:14][C:13](=[O:17])[CH2:12][NH:11]2)=[O:7])=[CH:4][CH:3]=1.C[O-].[Na+:22]>CO>[CH3:1][C:2]1[CH:3]=[CH:4][C:5]([C:6]([O:8][CH2:9][N:10]2[C:15](=[O:16])[N:14]([Na:22])[C:13](=[O:17])[CH2:12][NH:11]2)=[O:7])=[CH:18][CH:19]=1

Participants

4

Reactant 2

HCID 10942334Sodium MethoxideHCID 12780062HCID 12780062, compound

Product 1

HCID 178425907HCID 178425907, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

2-(4-Methylbenzoyloxymethyl)-3,5-dioxo-hexahydro-1,2,4-triazine (1.0 g) is dissolved in methanol (60 ml), and the mixture is added with sodium methoxide (0.21 g) and stirred at room temperature for 30 minutes. The methanol is removed in vacuo, and the resulting white crystals are thoroughly washed with ethanol to give 2-(4-methylbenzoyloxymethyl)-3,5-dioxo-4-sodio-hexahydro-1,2,4-triazine (Compound No. 74). Yield, 0.84 g (77.8%). M.P., 225°-235° C. (decomp.).

Workup

  1. customThe methanol is removed in vacuo
  2. washthe resulting white crystals are thoroughly washed with ethanol

Sources & evidence

ORD record
ord-44f5ae61552c43e991351d740ddb6eb1
Source dataset
uspto-grants-1981_10
Patent number
US04297129

Reaction notes

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