HCID 178526941, compound → HCID 178526973, compound

HRID 848640Notes

Reaction equation

HRID 848640 reaction equation
[OH2:1].[O:2]=[C:3]1[N:8]([Na:9])[C:7](=[O:10])[CH:6]=[N:5][NH:4]1>O.C(O)C.[Pt]=O>[OH2:2].[OH2:1].[O:2]=[C:3]1[N:8]([Na:9])[C:7](=[O:10])[CH2:6][NH:5][NH:4]1

Participants

5

Reactant 1

HCID 178526941HCID 178526941, compound

Product 1

HCID 178526973HCID 178526973, compound

Reagents, catalysts & solvents 3

HCID 82844Platinum oxide (PtO)CatalystHCID 702EthanolSolventHCID 962WaterSolvent

Procedure

3,5-Dioxo-4-sodio-2,3,4,5-tetrahydro-1,2,4-triazine monohydrate (770 mg) dissolved in water (60 ml) is hydrogenated for 4 hours in the presence of platinum oxide (100 mg) at atmospheric pressure. The catalyst is filtered off, and the filtrate is concentrated in vacuo to give a colorless transparent liquid. The liquid is dissolved in ethanol (30 ml), and the solvent is then removed in vacuo to give amorphous solids of 3,5-dioxo-4-sodio-hexahydro-1,2,4-triazine dihydrate (Compound No. 4). Yield, 850 mg (98.2%). Softening temperature, 122.3° C.

Workup

  1. filtrationThe catalyst is filtered off
  2. concentrationthe filtrate is concentrated in vacuo
  3. customto give a colorless transparent liquid
  4. customthe solvent is then removed in vacuo

Sources & evidence

ORD record
ord-eb59e34e835c404aadd0bc4c26631abd
Source dataset
uspto-grants-1981_10
Patent number
US04297129

Reaction notes

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