Phosphorus pentachloride → HCID 86735828, compound

HRID 848665Notes

Reaction equation

HRID 848665 reaction equation
[Cl:1][C:2]1[CH:3]=[C:4]([C:14]([OH:16])=O)[C:5]([CH2:11][O:12][CH3:13])=[CH:6][C:7]=1[N+:8]([O-:10])=[O:9].P(Cl)(Cl)(Cl)(Cl)[Cl:18]>C1C=CC=CC=1>[Cl:1][C:2]1[CH:3]=[C:4]([C:14]([Cl:18])=[O:16])[C:5]([CH2:11][O:12][CH3:13])=[CH:6][C:7]=1[N+:8]([O-:10])=[O:9]

Participants

4

Reactant 2

HCID 24819Phosphorus pentachlorideHCID 86735827HCID 86735827, compound

Product 1

HCID 86735828HCID 86735828, compound

Reagents, catalysts & solvents 1

HCID 241BenzeneSolvent

Procedure

A mixture of 4-chloro-α-methoxy-5-nitro-o-toluic acid (3.6 g.) and phosphorus pentachloride (3.0 g.) in 120 ml of benzene is refluxed for thirty minutes. The mixture is then concentrated in vacuo and the residue boiled with 200 ml of hexane and filtered hot. The filtrate is partially concentrated and chilled to give 2.5 g. of white solid with mp 63°-65°.

Workup

  1. temperatureis refluxed for thirty minutes
  2. concentrationThe mixture is then concentrated in vacuo
  3. filtrationfiltered hot
  4. concentrationThe filtrate is partially concentrated
  5. temperaturechilled
  6. customto give 2.5 g

Sources & evidence

ORD record
ord-fa347dcbadae44e2b78b16e93a9d7d65
Source dataset
uspto-grants-1981_10
Patent number
US04297127

Reaction notes

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