HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 4261464, compound → 1-(4-Chlorophenyl)-2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-carbonitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 4261464 | HCID 4261464 | — |
| Solvent | 1,2-Dichlorobenzene | HCID 7239 | — |
| Product | 1-(4-Chlorophenyl)-2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-carbonitrile | HCID 2821948 | — |
Reaction Steps
A mixture of 8.8 g (0.03 mol) of α-cyano-β-(4-chloroanilino)-N-ethoxycarbonylacrylamide and 40 ml of ortho-dichlorobenzene is heated at reflux. After about 2 hours, crystals appear and the mixture is allowed to cool to room temperature. The mixture is filtered to yield 5-cyano-1-(4-chlorophenyl)uracil, m.p. 236°-239°.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04297297 |
| Source dataset | uspto-grants-1981_10 |
| ORD ID | ord-5f29e2571ed8423bb285087692fc82c8 |
| Source note | uspto-grants-1981_10 |