Zincchloride → 3-pyridylmethyl N-(4-cyanophenyl)thiocarbamate zinc chloride

HRID 848714Notes

Reaction equation

HRID 848714 reaction equation
[Cl-:1].[Zn+2:2].[Cl-].[N:4]1[CH:9]=[CH:8][CH:7]=[C:6]([CH2:10][O:11][C:12](=[S:22])[NH:13][C:14]2[CH:19]=[CH:18][C:17]([C:20]#[N:21])=[CH:16][CH:15]=2)[CH:5]=1>COCCO>[Cl-:1].[Zn+2:2].[C:20]([C:17]1[CH:18]=[CH:19][C:14]([NH:13][C:12](=[S:22])[O:11][CH2:10][C:6]2[CH:5]=[N:4][CH:9]=[CH:8][CH:7]=2)=[CH:15][CH:16]=1)#[N:21].[Cl-:1]

Participants

4

Reactant 2

HCID 3007855Zincchloride2×HCID 12790266O-[(Pyridin-3-yl)methyl] (4-cyanophenyl)carbamothioate

Product 1

HCID 867365583-pyridylmethyl N-(4-cyanophenyl)thiocarbamate zinc chloride

Reagents, catalysts & solvents 1

HCID 80192-MethoxyethanolSolvent2×

Procedure

The zinc chloride metal salt complex of Example I is made by dissolving 3-pyridylmethyl-N-(4-cyanophenyl)thiocarbamate (2.69 g., 0.01 mole) in 75 ml. of methyl cellosolve and adding to this stirred solution; a solution of zinc chloride (0.68 g., 0.005 mole) in 10 ml. of methyl cellosolve. The resulting solution is stirred at room temperature for 18 hours. The solvent is removed in vacuo and the residue is slurried in 30 ml. of methanol and collected on a filter to give 2.5 g. melting at 174°-5° C. with decomposition.

Workup

  1. customThe solvent is removed in vacuo
  2. customof methanol and collected on
  3. filtrationa filter
  4. customto give 2.5 g

Sources & evidence

ORD record
ord-008010e9163e4c2093dcfc8c366678bc
Source dataset
uspto-grants-1981_10
Patent number
US04297342

Reaction notes

Loading…