HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methanesulfonic Acid → 7-n-butyloxymethyl-(1H,3H,5H)-(1)-benzopyrano-(2,3-d)-pyrimidine-4-one-2-thione
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methanesulfonic Acid | HCID 6395 | — |
| Reactant | 2-Hydroxy-5-(hydroxymethyl)benzaldehyde | HCID 53142 | — |
| Reactant | Thiobarbituric acid | HCID 2723628 | — |
| Solvent | 1-Butanol | HCID 263 | — |
| Product | 7-n-butyloxymethyl-(1H,3H,5H)-(1)-benzopyrano-(2,3-d)-pyrimidine-4-one-2-thione | HCID 20564257 | — |
Reaction Steps
To a solution of 5-hydroxymethyl-salicylaldehyde (5.8 g.) and 2-thiobarbituric acid (6 g.) in n-butanol (100 ml.) add methanesulfonic acid (10 ml.) and heat to reflux, with stirring, for 1 hour. Cool, filter and wash the solid with ethanol and ether to yield 7-n-butyloxymethyl-(1H,3H,5H)-(1)-benzopyrano-(2,3-d)-pyrimidine-4-one-2-thione.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04297355 |
| Source dataset | uspto-grants-1981_10 |
| ORD ID | ord-e2191dd56f2446eeb0103dd94f1827d4 |
| Source note | uspto-grants-1981_10 |