HCID 13151139, compound → HCID 57145906, compound

HRID 848765Notes

Reaction equation

HRID 848765 reaction equation
[NH2:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]([C:10]2[S:14][C:13]([NH:15][CH2:16][CH:17]([CH3:19])[CH3:18])=[N:12][C:11]=2[CH3:20])=[O:9])=[CH:4][C:3]=1[N+:21]([O-])=O>C(O)(=O)C>[NH2:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]([C:10]2[S:14][C:13]([NH:15][CH2:16][CH:17]([CH3:19])[CH3:18])=[N:12][C:11]=2[CH3:20])=[O:9])=[CH:4][C:3]=1[NH2:21]

Participants

3

Reactant 1

HCID 13151139HCID 13151139, compound

Product 1

HCID 57145906HCID 57145906, compound

Reagents, catalysts & solvents 1

HCID 176Acetic AcidSolvent

Procedure

7 g of 1-amino-2-nitro-4-(4-methyl-2-isobutylamino-5-thiazoloyl)-benzene are reduced with 40 g of stannous chloride in 150 ml of acetic acid analogously to Example 1. Oily 1,2-diamino-4-(4-methyl-2-isobutylamino-5-thiazoloyl)-benzene is obtained and this is used in the following step.

Sources & evidence

ORD record
ord-41489766065b499ab5de2a7514e5174b
Source dataset
uspto-grants-1981_10
Patent number
US04297365

Reaction notes

Loading…