Ethanethiol → HCID 12789793, compound

HRID 848791Notes

Reaction equation

HRID 848791 reaction equation
N12CCCC1=NCCC2.[CH2:10]1[CH2:15][CH:14]2[O:16][CH:13]2[CH2:12][CH2:11]1.[CH2:17]([SH:19])[CH3:18]>CO>[CH2:17]([S:19][CH:14]1[CH2:15][CH2:10][CH2:11][CH2:12][CH:13]1[OH:16])[CH3:18]

Participants

5

Reactant 3

HCID 6343EthanethiolHCID 9246Cyclohexene oxideHCID 763491,5-Diazabicyclo(4.3.0)non-5-ene

Product 1

HCID 12789793HCID 12789793, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

Following the addition of 4 ml of DBN (1,5-diazabicyclo-[4,3,0]-non-5-ene), 98.1 g (1 mole) of cyclohexane oxide (Aldrich) were added dropwise to 65 g of ethane thiol (1.05 moles) in 300 ml of methanol. The mixture was kept under reflux overnight in a steam bath, the reflux temperature rising from 325° K. to 338° K. After adjustment to pH~8 with carbon dioxide, the methanol was distilled off and the residue was fractionated in vacuo.

Workup

  1. temperatureunder reflux overnight in a steam bath
  2. customrising from 325° K
  3. customto 338° K
  4. distillationAfter adjustment to pH~8 with carbon dioxide, the methanol was distilled off

Sources & evidence

ORD record
ord-7ffeb1c1f2f740058d3cea42fe1632cd
Source dataset
uspto-grants-1981_10
Patent number
US04297439

Reaction notes

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