HuagongsheHuagongshe Chemistry Print Report · For research reference only
3,3-Dimethyl-1,2,3,4-tetrahydroquinoxalin-2-one → (4aR,8aS)-3,3-Dimethyloctahydroquinoxalin-2(1H)-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3,3-Dimethyl-1,2,3,4-tetrahydroquinoxalin-2-one | HCID 595203 | — |
| Catalyst | Rhodium | HCID 23948 | — |
| Product | (4aR,8aS)-3,3-Dimethyloctahydroquinoxalin-2(1H)-one | HCID 12886757 | — |
Reaction Steps
In a manner analogous with the foregoing, 3,3-dimethyl-3,4-dihydroquinoxalin-2-one is hydrogenated at about 130° C. and 1500 psi in the presence of rhodium (5%) on charcoal in 2 hours, to yield cis-3,3-dimethyl-decahydroquinoxalin-2-one.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04297497 |
| Source dataset | uspto-grants-1981_10 |
| ORD ID | ord-843f413a5bd64737935bdc445d0befc4 |
| Source note | uspto-grants-1981_10 |