Sodium Hydroxide → 2-Chloro-3-phenyl-4-methylsulfonylbenzoic acid

HRID 848987Notes

Reaction equation

HRID 848987 reaction equation
[Cl:1][C:2]1[C:11]([C:12]2[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=2)=[C:10]([S:18]([CH3:21])(=[O:20])=[O:19])[CH:9]=[CH:8][C:3]=1[C:4]([O:6]C)=[O:5].[OH-].[Na+]>CO>[Cl:1][C:2]1[C:11]([C:12]2[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=2)=[C:10]([S:18]([CH3:21])(=[O:20])=[O:19])[CH:9]=[CH:8][C:3]=1[C:4]([OH:6])=[O:5]

Participants

4

Reactant 2

HCID 14798Sodium HydroxideHCID 21183183Methyl 2-chloro-4-methylsulfonyl-3-phenyl-benzoate

Product 1

HCID 211831732-Chloro-3-phenyl-4-methylsulfonylbenzoic acid

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

Methyl 2-chloro-4-methylsulfonyl-3-phenyl-benzoate was hydrolyzed with sodium hydroxide in aqueous methanol solution and recovered using standard methodology to obtain the title compound, a white solid, which was used as an intermediate without further analysis.

Workup

  1. customrecovered

Sources & evidence

ORD record
ord-015919db9c06421787d5fb0700abc39b
Source dataset
uspto-grants-2000_01
Patent number
US06010981

Reaction notes

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