HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methanol → 3-(2-Quinazolinylmethoxy)benzyl chloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methanol | HCID 887 | — |
| Reactant | Chloroform | HCID 6212 | — |
| Reactant | 3-(2-Quinazolinylmethoxy)benzyl alcohol | HCID 54335963 | — |
| Solvent | Thionyl Chloride | HCID 24386 | — |
| Product | 3-(2-Quinazolinylmethoxy)benzyl chloride | HCID 54017678 | — |
Reaction Steps
To a solution of 1.00 g (3.76 mmol) of 3-(2-quinazolinylmethoxy)benzyl alcohol in 10 ml of CHCl3, 0.5 ml of SOCl2 was added, followed by stirring at room temperature for 15 hours. A small amount of MeOH was added to the reaction mixture and the solvents were distilled off under reduced pressure, whereby 1.08 g of 3-(2-quinazolinylmethoxy) benzyl chloride were obtained as white powder.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06011033 |
| Source dataset | uspto-grants-2000_01 |
| ORD ID | ord-6dbce0b12e824656bbaed1017af58bd2 |
| Source note | uspto-grants-2000_01 |