HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methanol → trans-3-[2-(7-Chloroquinolin-2-yl)ethenyl]benzyl chloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methanol | HCID 887 | — |
| Reactant | Chloroform | HCID 6212 | — |
| Reactant | trans-3-[2-(7-Chloroquinolin-2-yl)ethenyl]benzyl alcohol | HCID 10827738 | — |
| Solvent | Thionyl Chloride | HCID 24386 | — |
| Product | trans-3-[2-(7-Chloroquinolin-2-yl)ethenyl]benzyl chloride | HCID 19369489 | — |
Reaction Steps
To a solution of 813 mg (2.75 mmol) of trans-3-[2-(7-chloroquinolin-2-yl)ethenyl]benzyl alcohol in 40 ml of CHCl3, 1.0 ml of SOCl2 was added, followed by stirring at room temperature for 24 hours. A small amount of MeOH was added to the reaction mixture and the solvent was distilled off under reduced pressure, whereby trans-3-[2-(7-chloroquinolin-2-yl)ethenyl]benzyl chloride was obtained as pale yellow powder.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06011033 |
| Source dataset | uspto-grants-2000_01 |
| ORD ID | ord-4cb3d504de18416ea1c0eb408c2f02c8 |
| Source note | uspto-grants-2000_01 |