Ammonium Chloride → HCID 178479073, compound

HRID 849049Notes

Reaction equation

HRID 849049 reaction equation
CO[C:3]1[CH2:4][CH2:5][CH2:6][CH2:7][CH:8]([CH2:10][CH:11]=[CH:12][C:13]2[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=2)[N:9]=1.[Cl-:19].[NH4+:20]>CO>[ClH:19].[C:13]1([CH:12]=[CH:11][CH2:10][CH:8]2[NH:9][C:3](=[NH:20])[CH2:4][CH2:5][CH2:6][CH2:7]2)[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1

Participants

4

Reactant 2

HCID 25517Ammonium ChlorideHCID 54560967HCID 54560967, compound

Product 1

HCID 178479073HCID 178479073, compoundYield 47.5%

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

The product of Example 33 (0.50 g, 2.05 mmol) in 18 mL of MeOH was reacted with ammonium chloride (144 mg, 2.7 mmol) by the method of Example 5 to yield 258 mg (30%) of the title material.

Sources & evidence

ORD record
ord-1d3f31da0b7c4a7eb4d49cc9a3f6e4ea
Source dataset
uspto-grants-2000_01
Patent number
US06011028

Reaction notes

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