Ammonium Chloride → HCID 178461471, compound

HRID 849061Notes

Reaction equation

HRID 849061 reaction equation
CO[C:3]1[CH2:4][C@@H:5]([CH3:15])[C@H:6]([CH2:8][C:9]2[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=2)[N:7]=1.[Cl-:16].[NH4+:17]>CO>[ClH:16].[CH3:15][C@H:5]1[C@H:6]([CH2:8][C:9]2[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=2)[NH:7][C:3](=[NH:17])[CH2:4]1

Participants

4

Reactant 2

HCID 25517Ammonium ChlorideHCID 10560088HCID 10560088, compound

Product 1

HCID 178461471HCID 178461471, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

A solution of the title product of Example 63 (300 mg, 1.4 mmol) in MeOH (20 mL) was reacted with ammonium chloride (77 mg, 1.6 mmol) by the method of Example 5 followed by chromatography to generate the title material (240 mg, 75%).

Sources & evidence

ORD record
ord-28b9fa598b0a4e11a87016671b14cc99
Source dataset
uspto-grants-2000_01
Patent number
US06011028

Reaction notes

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