HuagongsheHuagongshe Chemistry Print Report · For research reference only
Cyanide → 2-[2-(1,3-Dioxolan-2-yl)ethyl]cyclohexanone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Cyanide | HCID 5975 | — |
| Reactant | Methyl 1-[2-(1,3-dioxolan-2-yl)ethyl]-2-oxocyclohexanecarboxylate | HCID 18800645 | — |
| Solvent | Dimethyl Sulfoxide | HCID 679 | — |
| Solvent | Water | HCID 962 | — |
| Product | 2-[2-(1,3-Dioxolan-2-yl)ethyl]cyclohexanone | HCID 10774339 | — |
Reaction Steps
The product of Example 102 was reacted with sod ,m cyanide (0.69 g, 14.1 mmoles) in 25 mL of DMSO at 160° C. for 12 hrs. The reaction mixture was then diluted to 700 mL with water and extracted with ethyl acetate/hexane (1:1). The solvent removed from the extracts to provide the title compound as oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06011028 |
| Source dataset | uspto-grants-2000_01 |
| ORD ID | ord-1895e359a3e34dcaadeb004c916994e9 |
| Source note | uspto-grants-2000_01 |