Benzenesulfonyl chloride → HCID 18800738, compound

HRID 849111Notes

Reaction equation

HRID 849111 reaction equation
O[N:2]=[C:3]1[CH2:8][CH2:7][CH2:6][CH2:5][CH:4]1[CH2:9][C:10]#[N:11].C1(S(Cl)(=O)=[O:19])C=CC=CC=1.[OH-].[Na+]>CC(C)=O.O>[O:19]=[C:3]1[NH:2][CH:4]([CH2:9][C:10]#[N:11])[CH2:5][CH2:6][CH2:7][CH2:8]1

Participants

5

Reactant 3

HCID 7369Benzenesulfonyl chlorideHCID 14798Sodium HydroxideHCID 73517215HCID 73517215, compound

Product 1

HCID 18800738HCID 18800738, compound

Reagents, catalysts & solvents 1

HCID 18366337Propan-2-one--water (1/1)Solvent

Procedure

The product of Example 150 is reacted with benzenesulfonyl chloride and sodium hydroxide in acetone/water by the method of Example 67 to generate the title compound.

Sources & evidence

ORD record
ord-23c5d13dfa9345a28979374a968bc48c
Source dataset
uspto-grants-2000_01
Patent number
US06011028

Reaction notes

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