HCID 178498469, compound → HCID 178498400, compound

HRID 849120Notes

Reaction equation

HRID 849120 reaction equation
[ClH:1].[NH:2]=[C:3]1[NH:9][CH:8]([CH2:10][CH:11]=[CH:12][C:13]2[CH:22]=[CH:21][C:20]([N+:23]([O-])=O)=[CH:19][C:14]=2[C:15]([O:17][CH3:18])=[O:16])[CH2:7][CH2:6][CH2:5][CH2:4]1>CO.[Pd]>[ClH:1].[ClH:1].[NH2:23][C:20]1[CH:21]=[CH:22][C:13]([CH:12]=[CH:11][CH2:10][CH:8]2[CH2:7][CH2:6][CH2:5][CH2:4][C:3](=[NH:2])[NH:9]2)=[C:14]([CH:19]=1)[C:15]([O:17][CH3:18])=[O:16]

Participants

4

Reactant 1

HCID 178498469HCID 178498469, compound

Product 1

HCID 178498400HCID 178498400, compound

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 887MethanolSolvent

Procedure

The title material of Example 161 in MeOH is hydrogenated over Pd on carbon in a standard Parr apparatus selectively reducing the nitro function to generate the title product.

Sources & evidence

ORD record
ord-10f1465f6bfd471d966ce244738ecd36
Source dataset
uspto-grants-2000_01
Patent number
US06011028

Reaction notes

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