HCID 178418361, compound → HCID 178478656, compound

HRID 849150Notes

Reaction equation

HRID 849150 reaction equation
[ClH:1].[N+:2]([C:5]1[CH:10]=[CH:9][CH:8]=[CH:7][C:6]=1[CH2:11][CH:12]1[NH:18][C:17](=[NH:19])[CH2:16][CH2:15][CH2:14][CH2:13]1)([O-])=O.[H][H]>C(O)C.[Pd]>[ClH:1].[ClH:1].[NH:19]=[C:17]1[NH:18][CH:12]([CH2:11][C:6]2[CH:7]=[CH:8][CH:9]=[CH:10][C:5]=2[NH2:2])[CH2:13][CH2:14][CH2:15][CH2:16]1

Participants

5

Reactant 2

HCID 178418361HCID 178418361, compoundHCID 178479045HCID 178479045, compound

Product 1

HCID 178478656HCID 178478656, compoundYield 155.9%

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 702EthanolSolvent

Procedure

The product of Example 270 (0.150 g, 0.59 mmol) was dissolved in ethanol and treated with 5% Palladium on Carbon under 5 psi of Hydrogen to give the title product (141 mg, 0.46 mmol).

Sources & evidence

ORD record
ord-b96350cb77e54335852213bc92adb6b9
Source dataset
uspto-grants-2000_01
Patent number
US06011028

Reaction notes

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