HuagongsheHuagongshe Chemistry Print Report · For research reference only
6-Benzylpyridin-2-amine → 2-Imino-6-cyclohexylmethylpiperidine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 6-Benzylpyridin-2-amine | HCID 93902 | — |
| Catalyst | Platinum oxide (PtO) | HCID 82844 | — |
| Solvent | Acetic Acid | HCID 176 | — |
| Product | 2-Imino-6-cyclohexylmethylpiperidine | HCID 178507545 | — |
Reaction Steps
The 2-amino-6-benzylpyridine product of Example 298 A was reduced in acetic acid under hydrogen atmosphere utilizing platinum oxide catalyst to afford 2-imino-6-cyclohexylmethylpiperidine as an oil. The oil was dissolved in 1N HCl and lyophilized to give a white solid. The solid was recrystallized from EtOAc to give the title product as white crystals.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06011028 |
| Source dataset | uspto-grants-2000_01 |
| ORD ID | ord-c54b6b59a77b4a6d895f822e4a0e7eee |
| Source note | uspto-grants-2000_01 |