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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 849271Generated: October 29, 2026

Tromethamine hydrochloride → 1-O-isobutyryl-beta-D-glucose

https://huagongshe.com/reaction/849271

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTromethamine hydrochlorideHCID 93573—
ReactantIsobutyrateHCID 165337—
ReactantMagnesium ChlorideHCID 5360315—
Reactant[(2R,3S,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methyl phosphono hydrogen phosphate;(2R,3S,4R,5R)-2,3,4,5,6-pentahydroxyhexanalHCID 23616595—
Product1-O-isobutyryl-beta-D-glucoseHCID 18660039—

Reaction Steps

A reaction mixture of 50 mM Tris-HCl (pH 7.0), 10 mM MgCl2, 10 mM dithiotheritol 10 mM uridine 5'-diphosphate glucose, 1 mM isobutyrate, 2 units of GTI activity is made up. Reaction is carried out for 2 hrs. at 37° C. 1-O-isobutyryl-β-D-glucose is formed.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06011145
Source datasetuspto-grants-2000_01
ORD IDord-77d2f0be8bb44df1b0405c1e74dd4b55
Source noteuspto-grants-2000_01