1,3-Propanediamine → tert-Butyl (3-aminopropyl)carbamate

HRID 849277Notes

Reaction equation

HRID 849277 reaction equation
[NH2:1][CH2:2][CH2:3][CH2:4][NH2:5].[C:6]([O:10][C:11](=O)[O:12]C(C)(C)C)([CH3:9])([CH3:8])[CH3:7]>>[CH3:7][C:6]([O:10][C:11](=[O:12])[NH:1][CH2:2][CH2:3][CH2:4][NH2:5])([CH3:9])[CH3:8]

Participants

3

Reactant 2

HCID 4281,3-PropanediamineHCID 10219638Carbonic acid, bis(1,1-dimethylethyl) ester

Product 1

HCID 2735700tert-Butyl (3-aminopropyl)carbamate

Procedure

In Step 1, 1,3-diaminopropane (II) is reacted with a di-t-butylcarbonate (III) to give 3- aminopropyl carbamic acid 1,1-dimethylethyl ester (IV).

Sources & evidence

ORD record
ord-6d46844ca3784a07944313855b9b46f3
Source dataset
uspto-grants-2000_01
Patent number
US06011168

Reaction notes

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