3-(Tributylstannyl)pyridine → HCID 178478617, compound

HRID 849396Notes

Reaction equation

HRID 849396 reaction equation
C([Sn](CCCC)(CCCC)[C:6]1[CH:7]=[N:8][CH:9]=[CH:10][CH:11]=1)CCC.[ClH:20].Br[C:22]1[CH:23]=[CH:24][C:25]2[N:31]([CH2:32][C:33]3[N:34]=[CH:35][NH:36][CH:37]=3)[CH2:30][CH2:29][N:28]([C:38]([C:40]3[C:49]4[C:44](=[CH:45][CH:46]=[CH:47][CH:48]=4)[CH:43]=[CH:42][CH:41]=3)=[O:39])[CH2:27][C:26]=2[CH:50]=1>>[ClH:20].[ClH:20].[ClH:20].[NH:36]1[CH:37]=[C:33]([CH2:32][N:31]2[C:25]3[CH:24]=[CH:23][C:22]([C:6]4[CH:7]=[N:8][CH:9]=[CH:10][CH:11]=4)=[CH:50][C:26]=3[CH2:27][N:28]([C:38]([C:40]3[C:49]4[C:44](=[CH:45][CH:46]=[CH:47][CH:48]=4)[CH:43]=[CH:42][CH:41]=3)=[O:39])[CH2:29][CH2:30]2)[N:34]=[CH:35]1

Participants

3

Reactant 2

HCID 34838483-(Tributylstannyl)pyridineHCID 1784796677-Bromo-2,3,4,5-tetrahydro-1-(1H-imidazol-4-ylmethyl)-4-(1-naphthalenylcarbonyl)-1H-1,4-benzodiazepine, hydrochloride

Product 1

HCID 178478617HCID 178478617, compoundYield 8%

Procedure

Example 67 was prepared as a yellow solid in 8% yield from Compound A of Example 37 and 3-(tributylstannyl)pyridine as described for Compound B of Example 37.

Sources & evidence

ORD record
ord-bdd221b9386d443e8705c0f439a3a45e
Source dataset
uspto-grants-2000_01
Patent number
US06011029

Reaction notes

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