反应详情

2 g (7 mmol) of ethyl 3-(2-bromoethoxy)-2-methylbenzoate and 1.1 g (7.3 mmol) of potassium thiomethanesulfonate are dissolved in 10 ml of abs. ethanol. The reaction mixture is refluxed for 20 hours. The solvent is then distilled off and the residue is taken up in methylene chloride and washed with water. The organic phase is dried over sodium sulfate and the solvent is removed. The useful product is purified by column chromatography.

1. temperatureThe reaction mixture is refluxed for 20 hours
2. distillationThe solvent is then distilled off
3. washwashed with water
4. dry with materialThe organic phase is dried over sodium sulfate
5. customthe solvent is removed
6. customThe useful product is purified by column chromatography