Hydrochloric Acid → HCID 19366854, compound

Participants

Reaction Steps

Part A: A solution of (18.13 g, 57 mmol) of N-acetyl-β-(4-methoxyphenylsulfonyl)-D,L-alanine methyl ester in 125 mL concentrated hydrochloric acid and 125 mL of glacial acetic acid was refluxed for several hours under nitrogen atmosphere. The contents were concentrated by rotory evaporation to yield a crude solid which was slurried in dry toluene and filtered to yield 14.3 g of β-(4-methoxyphenylsulfonyl)-D,L-alanine hydrochloride as a white crystalline solid.

Provenance & Evidence