HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl iodide → (E)-methyl 3-(3-methoxyphenyl)acrylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl iodide | HCID 6328 | — |
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | 3-Methoxycinnamic Acid | HCID 637668 | — |
| Solvent | Acetone | HCID 180 | — |
| Product | (E)-methyl 3-(3-methoxyphenyl)acrylate | HCID 11041597 | — |
Reaction Steps
A mixture of (E)-3-(3-methoxyphenyl)acrylic acid (3.56 g, 20 mmol). K2CO3 (3.1 g, 22 mmol), and iodomethane (4.0 g, 28 mmol) in acetone (20 mL) was heated to 70° C. for 16 hours. The mixture was concentrated and partitioned between water and ethyl acetate to afford the crude title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08846951B2 |
| Source dataset | uspto-grants-2014_09 |
| ORD ID | ord-a6285a79c1b34b64965786eeecdd546f |
| Source note | uspto-grants-2014_09 |