HCID 131731907, compound → HCID 86653466, compound

HRID 84965Notes

Reaction equation

HRID 84965 reaction equation
O[C:2]1[CH:7]=[C:6]([O:8][CH3:9])[CH:5]=[CH:4][C:3]=1[C@H:10]1[C@H:14]([CH2:15][CH2:16][OH:17])[CH2:13][N:12]([C:18]([O:20][C:21]([CH3:24])([CH3:23])[CH3:22])=[O:19])[CH2:11]1.OC1C=CC=C(OC)C=1[C@H]1[C@H](CCO)CN(C(OC(C)(C)C)=O)C1>>[CH3:9][O:8][C:6]1[CH:5]=[CH:4][C:3]2[C@H:10]3[CH2:11][N:12]([C:18]([O:20][C:21]([CH3:24])([CH3:23])[CH3:22])=[O:19])[CH2:13][C@@H:14]3[CH2:15][CH2:16][O:17][C:2]=2[CH:7]=1

Participants

3

Reactant 2

HCID 131731907HCID 131731907, compoundHCID 131731909trans-Tert-butyl 3-(2-hydroxy-6-methoxyphenyl)-4-(2-hydroxyethyl)pyrrolidine-1-carboxylate

Product 1

HCID 86653466HCID 86653466, compound

Procedure

The title compound was prepared as described in Example 272E substituting the product from Example 280D for the product from Example 272D.

Sources & evidence

ORD record
ord-89e9c46099a84ab2b5d591d3cf89c35b
Source dataset
uspto-grants-2014_09
Patent number
US08846951B2

Reaction notes

Loading…