HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → 2-Nitro-4-(pentafluorosulfanyl)aniline
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | 4-Acetamido-3-nitrophenylsulphur pentafluoride | HCID 54537779 | — |
| Solvent | 1,4-Dioxane | HCID 31275 | — |
| Product | 2-Nitro-4-(pentafluorosulfanyl)aniline | HCID 45933650 | 98.7% |
Reaction Steps
4-Acetamido-3-nitrophenylsulphur pentafluoride (29.0 g) was heated at reflux with hydrochloric acid (6N) and dioxan for 40 minutes and concentrated to low volume, basified with sodium carbonate solution and extracted (ether). The extract was washed (water), dried (magnesium sulphate) and evaporated to give 4-amino-3-nitrophenylsulphur pentafluoride (24.7 g), m.p.132-135° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06013805 |
| Source dataset | uspto-grants-2000_01 |
| ORD ID | ord-ac3027f2866b4a269207c20577b3352a |
| Source note | uspto-grants-2000_01 |